The Humane Society of the Ozarks' overall mission is to prevent cruelty to animals and to educate about responsible pet ownership. We achieve this goal through various programs, including education programs in local schools, spay/neuter assistance, emergency and shelter outreach, and cruelty prevention and investigation.

Executive Director - Carmen Nelson
Office Manager - Linda Gershon

The Humane Society of the Ozarks, Inc. (HSO) has a Board of Directors that oversees the operation of the organization. The current Board of Directors for the HSO is as follows:
- Jamey Sims - President
- Chris Blake - Vice President
- Scott Hall - Secretary
- Jeff Dunn - Treasurer
- LeAnn Box
- Linda Gaddy
- Ronnie Robinson
- Jenny Shreve
- Cristy Smith
- Georgia Grand
- Bonnie LaGrone
- Melissa Owings
- Karen Koch
- Priscilla Kumpe
- Stacey Fraser